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A multidisciplinary team of researchers from the School of Agricultural Engineering, University of Castilla-La Mancha (UCLM) - assigned to Group Health and Biotechnology (Sage) - Regional Center of Animal Selection and Reproduction (CERSYRA) of valdepeñas Board of the Centre food cart business for Research and Food Technology (CITA) of Aragon and the National Institute of Agricultural and Food Research and Technology food cart business (INIA) has demonstrated food cart business the role of HSP90AA1 gene in DNA integrity food cart business of sperm in conditions heat stress.
A multidisciplinary team of researchers from the School of Agricultural Engineering, University of Castilla-La Mancha (UCLM) - assigned to Group Health and Biotechnology (Sage) - Regional Center of Animal Selection and Reproduction (CERSYRA) of valdepeñas Board of the Centre for Research and Food Technology (CITA) of Aragon and the National Institute of Agricultural and Food Research food cart business and Technology (INIA) has demonstrated the role of HSP90AA1 gene in DNA integrity of sperm in conditions heat stress.
To do have examined the effects of exposure to high temperatures during the process of spermatogenesis (sperm food cart business production) in three groups of male with different genotype to a mutation in the DNA sequence located food cart business in the promoter of said gene, as has UCLM reported in a statement.
The results of the study showed two critical periods: from 29 to 35 days prior to semen collection, coinciding with meiosis I (cell division) and between 7-14 days prior to collection of semen, corresponding with late stages of meiosis II and initiating maturation epididymal (testicular). Thus, the researchers observed as exposure to high temperatures - the summer months in Castilla-La Mancha - produces a significant increase in DNA damage of sperm, "which could translate into a reduction in fertility animal "as indicated investigators ETSIA Albacete.
These results food cart business also showed that there was a different food cart business response to heat stress depending on the genotype of the animals, according to a timely change of cytosine to guanine in DNA sequence located food cart business in the promoter of the gene HSP90AA1. "Thus, male carriers of the GG-660 genotype had higher levels of DNA breaks his sperm, which makes these more susceptible to high ambient temperatures animals," according to the authors.
The results from this research can be applied directly, since the characterization of the genotype for HSP90AA1 gene could allow the selection of resistant animals high ambient temperatures, with good reproductive performance in adverse conditions of temperature and humidity. food cart business "These food cart business findings food cart business also gain importance given the current concerns about the consequences of global warming, and that is reflected in the new framework program Horizon 2020, which includes food cart business the study of climate change as a key objective," pointed out .
In this paper the researchers food cart business Manuel Ramon, Judit Salces-Ortiz, Carmen food cart business Gonzalez, M. took part Dolores Pérez-Guzmán, J. Julián Garde Olga Garcia Álvarez Alejandro Maroto-Morales Jorge H. Calvo, M. Magdalena Serrano.
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